P. Nogly
Dioscuri Centre for Structural Dynamics of Receptors, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland; przemyslaw.nogly@uj.edu.pl
Chloride transport is an essential process maintaining ion balance across cell membranes, cell growth, and neuronal action potentials. However, the molecular mechanism of the transport remains elusive. Among...
Högbom, M 1
- Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden.
High resolution structure determination methods suffer from problems with radiation damage. This is particularly problematic for radiation sensitive states such as high-valent metal sites and radicals. From a chemical perspective this means that some of the most relevant states for...
The transition from 3rd to 4th generation synchrotrons—featuring diffraction-limited storage rings—has significantly expanded future possibilities for macromolecular crystallography (MX). These upgrades, characterized by reduced source divergence and increased electron bucket capacity, have boosted brilliance by up to two orders of magnitude. As a result, next-generation MX beamlines, such as...
In standard crystallographic refinement of proteins, the experimental data are normally not enough to unambiguously decide the positions of all atoms. Therefore, the crystallographic data are supplemented by a set of empirical restraints that ensure that bond lengths and angles make chemical sense. To obtain more accurate results, we have suggested that this potential can be replaced by more...
The rise of 4th generation sources, including the MAX IV Laboratory 3 GeV ring, has enabled new possibilities to study dynamics using crystallography. The MicroMAX beamline is a new beamline focussed on providing optimal X-ray characteristics for serial (SSX) and time-resolved (TR-SSX) crystallography at MAX IV [1]. The beamline emphasizes a flexible sample environment for standard and bespoke...
The rise of 4th generation sources, including the MAX IV Laboratory 3 GeV ring, has enabled new possibilities to study dynamics using crystallography. The MicroMAX beamline is a new beamline focussed on providing optimal X-ray characteristics for serial (SSX) and time-resolved (TR-SSX) crystallography at MAX IV [1]. The beamline emphasizes a flexible sample environment for standard and bespoke...
The rise of 4th generation sources, including the MAX IV Laboratory 3 GeV ring, has enabled new possibilities to study dynamics using crystallography. The MicroMAX beamline is a new beamline focussed on providing optimal X-ray characteristics for serial (SSX) and time-resolved (TR-SSX) crystallography at MAX IV [1]. The beamline emphasizes a flexible sample environment for standard and bespoke...
