Name: Scientific achievements through serial crystallography
Start: 2025-09-22T11:00:00+02:00
End: 2025-09-24T14:00:00+02:00
Location: LINXS at The Loop

Scientific achievements through serial crystallography

from Monday, September 22, 2025 (11:00 AM) to Wednesday, September 24, 2025 (2:00 PM)

Monday, September 22, 2025
11:00 AM Arrival: Registration & Lunch
Registration & Lunch
11:00 AM - 1:00 PM
Contributions

11:00 AM Registration

12:00 PM Lunch
1:00 PM Monday: Afternoon
Afternoon
1:00 PM - 5:15 PM
Contributions

1:00 PM Welcome (Science Director Joachim Schnadt & MicroMAX Spokesperson Richard Neutze) - Joachim Schnadt (MAX IV Laboratory) Richard Neutze (University of Gothenburg)

1:10 PM Some questions can only be answered by time: how time-resolved crystallography reshapes structural biology - Tobias Weinert (Paul Scherrer Institute)

1:40 PM The potential for serial crystallography in drug discovery - Helena Käck

2:40 PM From Static to Dynamic: Evolving Methods in Protein Structure Determination - Aina Cohen (Stanford Synchrotron Radiation Lightsource)

3:10 PM Serial crystallography at the beamline P11, PETRA III - Guillaume Pompidor (DESY)

3:25 PM Time-resolved crystallography of light-driven ion transporters at synchrotrons and free electron lasers - Kirill Kovalev (EMBL-Hamburg)

4:30 PM Electrostatically Gated Enzyme Dynamics During Catalysis - Mark Wilson (University of Nebraska–Lincoln)

5:00 PM Current and future capabilities for serial and time resolved crystallography at Diamond microfocus beamline VMXi - Juan Sanchez Weatherby (Diamond Light Source)
5:15 PM Posters: Mingle & food
Mingle & food
5:15 PM - 7:50 PM
Contributions

5:15 PM Posters & mingle food (Poster list with abstracts below)

5:30 PM In crystallo study of the reaction mechanism in a family B DNA polymerase - Vimal Parkash (Umeå University)

5:40 PM Time-resolved serial crystallograhy to capture reaction intermediates of a glucuronyl esterase - Gabrielle Wehlander (University of Gothenburg)

5:50 PM Comprehensive Support for Serial Crystallography at the European XFEL - Huijong Han (European XFEL)

6:00 PM Development of new data processing methods for serial time-resolved crystallography - Rachel Tang (Diamond Light Source)

6:10 PM Structural studies of the human drug-metabolising protein CYP3A4 - Johan Glerup (University of Gothenburg)

6:20 PM Scientific opportunities for Serial Crystallography at ALBA synchrotron - Isidro Crespo (ALBA-CELLS) Xavi Carpena i Vilella (ALBA-CELLS)

6:30 PM Reducing data volume with X-ray Laue diffraction - Kah Chee Pow (Spallation Neutron Source Science Center)

6:40 PM Serial X – Simple Solutions for Serial Synchrotron Crystallography - Yanyan Chen (Serial X AB)

6:50 PM Experimental estimation of copper-ligand length precision in a model fungal LPMO under redox cycling and saccharide binding - Zhiyu Huang (University of Copenhagen)

7:00 PM Time and dose resolved crystallography to control and capture redox states in heme peroxidases - Michael Hough (Diamond Light Source)

7:10 PM Standard Sample Preparation and Characterization for Serial Crystallography - Christina Schmidt (European XFEL)

7:20 PM Laser and Spectroscopic Capabilities at MicroMAX - Manoop Chenchiliyan (MAX IV Laboratory) Sofia M. Kapetanaki (MAX IV Laboratory)

7:30 PM MicroMAX - A beamline with time-resolved macromolecular crystallography capabilities at the MAX IV Laboratory - Jie Nan et al (MAX IV Laboratory)

7:40 PM Fragment Based Active Site Exploration of Polyurethane Degrading Enzymes for Structure-guided Protein Engineering - Deniz Bicer (Aarhus University)
Tuesday, September 23, 2025
8:30 AM Tuesday: Morning & early afternoon
Morning & early afternoon
8:30 AM - 2:30 PM
Contributions

9:00 AM Time-resolved X-ray crystallography on membrane proteins: Watching ions moving in time and space - Przemyslaw Nogly (Jagiellonian University in Krakow)

9:30 AM Using advanced crystallographic approaches to resolve how orange carotenoid protein photocycle works - Volha Chukhutsina (Vrije Universiteit Amsterdam)

10:00 AM GPCRs as Targets for Serial Crystallography - Hannah Glover (leadXpro)

10:45 AM Serial femtosecond crystallography of high-valent metal sites and protein radicals - Martin Högbom (Stockholm University)

11:15 AM Modeling X-ray-Induced Heating at 4th-Generation MX Beamlines - Michal Kepa (Paul Scherrer Institute)

11:45 AM Quantum refinement used for time-resolved crystallography - Gayathri Yuvaraj (Lund University)

1:30 PM MicroMAX - Overview - Jie Nan (MAX IV Laboratory)

1:50 PM Sample delivery at MicroMAX - Dean Lang (MAX IV Laboratory)

2:10 PM Data analysis at MicroMAX - Cecilia Casadei (MAX IV Laboratory)
2:30 PM Tuesday afternoon
2:30 PM - 5:00 PM
Contributions

2:30 PM Panel discussion - John Beale (Paul Scherrer Institute)

3:45 PM MAX IV visit
7:00 PM Tuesday afternoon: Symposium Dinner
Symposium Dinner
7:00 PM - 10:00 PM
Wednesday, September 24, 2025
8:30 AM Morning: Wednesday
Wednesday
8:30 AM - 1:00 PM
Contributions

9:00 AM Investigating enzyme mechanisms by multidimensional crystallography - Pedram Mehrabi (University of Hamburg)

9:30 AM Time-resolved macromolecular crystallography studies of AmpCEC using synchrotron and XFEL radiation - Emily Freeman (University of Oxford)

10:15 AM Turning Up the Heat on Dynamic Proteins with Temperature-Jump X-ray Crystallography - Michael Thompson (University of California, Merced)

10:45 AM Serial Techniques for Weakly Scattering, In-Situ, and Dynamic Systems - Mark Warren (Diamond Light Source)

11:15 AM Serial Microsecond Crystallography with the ESRF Extremely Brilliant Source - Daniele de Sanctis (ESRF - The European Synchrotron)

11:45 AM Wrap-up
1:00 PM End of Symposium: Start of TR+ Workshop
Start of TR+ Workshop
1:00 PM - 2:00 PM

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