Welcome to the LINXS mAb Final Meeting in Lund on September 25-27, 2024!
The LINXS mAb Final Meeting will be organized as a face-to-face event at the LINXS venue (IDEON Delta 5, Scheelevägen 19, 5th floor) in Lund.
We welcome all members of the LINXS Antibody Consortium as well as all PhD-students / postdocs / researchers that are involved in the LINXS mAb project to participate.
Our Final Meeting consists of 2 Parts (you can register either for Part I or for Part I and Part II during registration):
Part I of the event (Sept. 25 to 26, lunch to lunch) comprises scientific presentations.
Part II (extension to September 27, lunchtime) is reserved for all those of us who want to continue discussing/working on data, common publications, potential future grant applications, and in general the future of our Antibody Consortium, after the end of the official running time at LINXS (end of 2024).
There will be a limited number of seats available (max. 40). Coffee, lunch and dinner will be served on-site.
Registration deadline is June 30th, 2024.
Location: LINXS venue, IDEON Building: Delta 5 (5th floor), Scheelevägen 19, Lund
Programme
Part 1 (open to public)
Wednesday afternoon, 25 September 2024
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12:15 – 13:15 |
Lunch |
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13:15 – 13:30 |
Welcome: Anna Stradner (Lund University & LINXS) |
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13:30 – 14:00 |
OP1: Robin Curtis (Univ. Manchester) “What can be learned from dilute solutions measurements of protein-protein interactions” |
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14:00 – 14:30 |
OP2: Peter Schurtenberger (Lund University) “Towards an improved colloid model for antibodies in solution” |
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14:30 – 15:00 |
OP3: Yun Liu (NIST, USA) “Protein-protein interactions and high-concentration solution viscosity of a monoclonal antibody: the effect of temperature” |
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15:00 – 15:30 |
Coffee break |
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15:30 – 16:00 |
OP4: Ralf Biehl (FZ Jülich) “Antibody domain dynamics: Search and Attack motions?” |
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16:00 – 16:30 |
OP5: Sergei Grudinin (Univ. Grenoble) “Atomic-scale modeling of antibodies: linking SAXS experiments with molecular simulations” |
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16:30 – 17:00 |
OP6: Emanuela Zaccarelli (Roma La Sapienza) & Fabrizio Camerin(Lund University) “Updates on coarse-grained antibody modelling” |
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17:00 – 17:30 |
OP7: Frank Delaglio (NIST, USA) “Characterizing mAb Expression, Structure, and Excipient Interactions by NMR Spectroscopy Using Spectral Modeling, Chemometrics, and Machine Learning” |
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17:30 – 18:00 |
OP8: Jure Cerar / Barbara Brannetti (Novartis, Basel) “The journey of a biologics from research to development: in-silico perspective” |
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18:00 – |
Dinner |
Thursday morning, 26 September 2024
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09:00 – 09:30 |
OP9: Andreas Stadler (FZ Jülich) “Multiscale dynamics of the NIST mAb studied by quasielastic neutron scattering” |
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09:30 – 10:00 |
OP10: Margarita Kruteva (FZ Jülich) “Diffusion NMR on monoclonal Antibodies” |
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10:00 – 10:30 |
OP11: Marco Polimeni (Lund University) “Modelling biomolecular interactions of mAb solutions” |
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10.30 – 11:00 |
Coffee break |
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11:00 – 11:10 |
Final Remarks Novartis: Karoline Bechtold-Peters (Novartis, Basel) |
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11:10 – 11:20 |
Final Remarks NIST: Katharina Yandrofski (NIST, USA) |
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11:20 – 12:15 |
Round table discussions: Lessons learned and loose ends (Dieter Richter (FZ Jülich) (chair); Karoline Bechtold-Peters (Novartis); Katharina Yandrofski / Yun Liu (NIST); Mikael Lund (Lund University)) |
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12:15 – 13:00 |
Lunch |
Part 2 (not open to public – for mAb consortium only)
Thursday afternoon, 26 September 2024
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14:00 – 18:00 |
Working on data and common publications; discussions on plans for future incl. potential grant applications |
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18:00 - |
Dinner |
Friday morning, 27 September 2024
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09:00 – 12:00 |
Working on data and common publications; discussions on plans for future incl. potential grant applications |
|
12:00 – 13:00 |
Lunch |
