(See Overview page, at the bottom, for a PDF version of the programme)
Wednesday October 26 (at LINXS)
12:00 Lunch at LINXS
13:00 Introduction
13:10 Kresten Lindorff-Larsen, University of Copenhagen
Combining biomolecular simulations with time-dependent and time-resolved experiments
13:40 Magnus Andersson, Umeå University
Tracking ATP-dependent membrane protein regulation in real time
14:00 James Fraser, University of California San Francisco, USA
Finding new inhibitors for SARS CoV 2 Macrodomain with X-ray fragment screening, neutrons, and entropy
14:30 Coffee Break
15:00 Kristine Steen Jensen, Lund University
Early events in SOD1 amyloid formation
15:30 Angus Robertson, Lund University
Pressure-Jump NMR investigations of aggregating systems
15:50 Volha Chukhutsina, Vrije Universiteit Amsterdam, the Netherlands
Cryotrapping photocycle intermediates to resolve how lazy photoreceptors work
16:20 Coffee Break
16:40 Thomas Barends, Max-Planck Institute for Medical Research, Heidelberg, Germany
Time-resolved serial femtosecond crystallography of a photoenzyme: pitfalls and progress
17:10 Discussion (moderated by Allen Orville, Diamond Light Source)
18:00 Poster session
19:00 End of 1st day
Thursday October 27 (morning at LINXS)
09:00 Jörg Standfuss, Paul Scherrer Institute, Switzerland
Release of a photopharmacological drug from tubulin over eleven orders of magnitude in time
09:30 Martin Weik, Institut de Biologie Structurale, Grenoble, France
Photoswitchable fluorescent proteins: what we have learnt through time-resolved serial crystallography
10:00 Jacques-Philippe Colletier, Institut de Biologie Structurale, Grenoble, France
Use of short X-ray pulses to probe the structural dynamics of the orange carotenoid protein (OCP)
10:30 Coffee Break
10:50 Ulf Ryde, Lund University
Improving and interpreting crystal structures with quantum refinement
11:20 Discussion (moderated by Allen Orville, Diamond Light Source)
12:00 Lunch at LINXS and transport to MAX IV Laboratory
Thursday October 27 (afternoon at MAX IV Laboratory)
14:00 Gisela Brändén, University of Gothenburg
XFEL- and synchrotron-based serial crystallography studies of the membrane-bound proton pump cytochrome c oxidase
14:30 Sam Horrell, Diamond Light Source, UK
Time-resolved X-ray Crystallography at Diamond Light Source
14:50 Michal Kepa, Paul Scherrer Institute, Switzerland
Towards automation of serial crystallography using a multi-reservoir high viscosity extruder
15:10 Introduction to MicroMAX (Oskar Aurelius, MAX IV Laboratory)
15:20 Discussion (moderated by Allen Orville, Diamond Light Source)
15:50 Coffee Break
16:10 Visit of MAX IV & MicroMAX
17:00 Break before dinner
19:00 Dinner in Lund ("Gamla Franska", Saluhallen Lund Mårtenstorget 1)
Friday October 28 (at LINXS)
09:00 Manuel Maestre-Reyna, National Taiwan University (remote presentation)
Watching DNA repair via time-resolved serial femtosecond crystallography
09:30 Alessandra Henkel, CFEL/DESY, Hamburg, Germany
CFEL TapeDrive 2.0: Conveyor belt-based sample delivery system for multi-dimensional serial crystallography
09:50 Coffee Break
10:20 Stephen Muench, University of Leeds, UK
The development and application of time-resolved single particle cryoEM
10:50 Gergely Katona, University of Gothenburg
Deformation networks in protein crystals revealed by steady state and THz pump - X-ray probe crystallography
11:20 Discussion (moderated by Allen Orville, Diamond Light Source)
12:00 Lunch
13:00 End of Meeting
