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2nd LINXS Symposium on Integrative Structural Biology

9–11 Oct 2019
Kulturen
Europe/Stockholm timezone

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Session

Keynotes and Short talks 5

10 Oct 2019, 14:00
Auditorium (Kulturen)

Auditorium

Kulturen

Tegnérsplatsen 6 223 50 Lund, Sweden

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  1. 16. Keynote 7, Prof. Mei Hong: Structure and Dynamics of Amyloid Proteins from Solid-State NMR: Glucagon & Tau
    Prof. Mei Hong (MIT, USA)
    10/10/2019, 14:00

    Protein misfolding into amyloid fibrils is common not only in neurodegenerative diseases but also in pharmaceutical sciences, where many peptide-based drugs have the tendency to fibrillize, thus impeding solution formulation of the drug. Using solid-state NMR spectroscopy, we have investigated the structure and dynamics of two amyloid fibrils, one formed by the peptide hormone glucagon, which...

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