Conveners
Transport Processes: Morning session
- Emma Sparr (Division of Physical Chemistry, Chemistry Department, Lund University, P.O. Box 124, 22100 Lund, Sweden)
Transport Processes: Morning session
- Emma Sparr (Division of Physical Chemistry, Chemistry Department, Lund University, P.O. Box 124, 22100 Lund, Sweden)
Pore-spanning membranes (PSMs) are well-suited to investigate single lipid diffusion as well as lipid domain diffusion. Recent findings have highlighted the dynamic nature of such domains in the plasma membrane and the key role of the underlying cytoskeleton meshwork in stabilizing them. We used porous substrates with different pore radii serving as a static meshwork to modulate the size of...
The phospholipid bilayer is the basic structural motif of most biological membranes. As such, many biological processes occur within or in the proximity of the cell membrane, and therefore, interest in the properties and behavior of lipids in membranes is considerable. For example, it is found that in nature the lipid distribution across the inner and outer leaflet of cell membranes is...
It is today clear that lipids are involved in many physiological functions that go beyond the traditional view of compartmentalisation of the cell and its organelles. The metabolism of lipids including cholesterol involves the production, in the liver, of lipid carrying particles known as lipoproteins. Lipoproteins are nano emulsion like particles composed of fats and proteins (named...
The highly dynamic nature of lipid membranes is crucial to accommodate the numerous types of biological molecules embedded within the cell membrane and help facilitate their functions. It is therefore essential to understand how lipid membrane dynamics are affected by different types of inclusions from a molecular level. One of the most important dynamic is the bending elastic modulus that...
We report on diffusion of hydration between phospholipid membranes using incoherent quasi-elastic neutron scattering (QENS) and computer simulations [1]. The combination of a well-aligned stack of DMPC membranes with the large, 2-dimensional detectors available at the neutron spectrometer Let (ISIS, UK) allows for simultaneous access to water motions lateral and perpendicular to the membranes....
