Registration for onsite participation is closed.

Registration for online participation (via zoom) is open until Sunday, September 25, 2022, at midnight.

Welcome to the LINXS mAb Midterm Meeting in Lund on September 27/28, 2022!

The LINXS mAb Midterm Meeting (lunch-to-lunch) will be organized as a face-to-face event at the LINXS venue (IDEON Delta 5, Scheelevägen 19, 5th floor) in Lund.

We welcome all members of the LINXS Antibody Consortium as well as all PhD-students / postdocs / researchers that are involved in the LINXS mAb project to participate.

There will be a limited number of seats available. Coffee, lunch and dinner will be served on-site.

Registration deadline is September 25, 2022.

Location: LINXS venue, IDEON Building: Delta 5 (5th floor), Scheelevägen 19, Lund

Program

Tuesday, 27 September 2022
12:00 – 13:00 Lunch
13:00 – 13:15 Welcome, introduction
13:15 – 13:45 WP 1: Robin Curtis (on-line), “Separating out effects of
deuterated water on protein-protein electrostatic interactions
and other short-ranged forces”
13:45 – 14:15 WP 2: Peter Schurtenberger, “Solution structure and collective
dynamics – Insight from a combination of SAXS, SLS, DLS and
microrheology”
14:15 – 14:45 NIST: Yun Liu, "Dynamics of the NISTmAb in solution:
concentration and temperature effects"
14:45 – 15:15 WP 4: Sergei Grudinin, “Atomic-scale integrative modeling of
antibodies”
15:15 – 15:45 Coffee break
15:45 – 16:15 NIST/WP 4: Christina Bergonzo (on-line), “Characterizing the
structure and dynamics of the NISTmAb Fc domain”
16:15 – 18:00 Discussion on open problems, new findings, plans
18:30 – Dinner

Wednesday, 28 September 2022
09:00 – 09:15 WP 2/WP 3: Andreas Stadler, “QENS, data analysis and the use of complementary spectrometers for the study of mAb dynamics”
09:15 – 09:30 WP 2/WP 3: Margarita Kruteva, “Large scale dynamics of mAb probed by PFG NMR”
09:30 – 10:00 WP 2/WP 3: Ralf Biehl, “mAb domain dynamics observed by NSE”
10:00 – 10:30 WP 4: Emanuela Zaccarelli, “Coarse-grained colloidal models for antibodies”
10.30 – 11:00 Coffee break
11:00 – 11:15 Update from Novartis: Karoline Bechtold-Peters
11:15 – 11:30 Feedback from NIST: John Schiel and/or Katharina Yandrovski
11:30 – 12:00 Discussion, next steps
12:00 – 13:00 Lunch