SwedNESS PhD school: Neutrons in Life Science and Biomaterials
from
Monday 14 June 2021 (08:30)
to
Friday 18 June 2021 (16:00)
Monday 14 June 2021
08:30
Introduction - Tommy Nylander
Introduction - Tommy Nylander
08:30 - 08:45
08:45
Protein unfolding and degradation
-
Dr. Frank Gabel, IBS, Grenoble, France
Protein unfolding and degradation
Dr. Frank Gabel, IBS, Grenoble, France
08:45 - 09:45
09:45
Break & Discussion
Break & Discussion
09:45 - 10:00
10:00
Protein crystallization
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Dr. Esko Oksanen, ESS ERIC, Lund, Sweden
Protein crystallization
Dr. Esko Oksanen, ESS ERIC, Lund, Sweden
10:00 - 11:00
11:00
Break & Discussion
Break & Discussion
11:00 - 11:15
11:15
Biophysical studies – key for exploiting the potential of neutrons
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Prof. Sara Snogerup Linse, Lund University
Biophysical studies – key for exploiting the potential of neutrons
Prof. Sara Snogerup Linse, Lund University
11:15 - 12:15
12:15
LUNCH
LUNCH
12:15 - 13:00
13:00
Project pitches from participating students describing their own project.
13:00 - 14:00
14:00
Break & Discussion
Break & Discussion
14:00 - 14:15
14:15
Introducing proposal writing for beam time. Preparation for individual proposals
14:15 - 15:15
15:15
Break & Discussion
Break & Discussion
15:15 - 15:30
15:30
Protein expression for neutron studies
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Prof. Trevor Forsyth, ILL/Keele University, Grenoble, France
Protein expression for neutron studies
Prof. Trevor Forsyth, ILL/Keele University, Grenoble, France
15:30 - 16:30
Tuesday 15 June 2021
08:45
Fiber diffraction, structure determination
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Prof. Trevor Forsyth, ILL/Keele University, Grenoble, France
Fiber diffraction, structure determination
Prof. Trevor Forsyth, ILL/Keele University, Grenoble, France
08:45 - 09:45
09:45
Break & Discussion
Break & Discussion
09:45 - 10:00
10:00
Dynamics of biomolecules from proteins to lipids
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Dr. Victoria Garcia Sakai, ISIS, Rutherford Appleton Lab, UK
Dynamics of biomolecules from proteins to lipids
Dr. Victoria Garcia Sakai, ISIS, Rutherford Appleton Lab, UK
10:00 - 11:00
11:00
Break & Discussion
Break & Discussion
11:00 - 11:15
11:15
EXERCISE: Planning dynamics experiments for lipids.
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Dr. Victoria Garcia Sakai, ISIS, Rutherford Appleton Lab, UK
EXERCISE: Planning dynamics experiments for lipids.
Dr. Victoria Garcia Sakai, ISIS, Rutherford Appleton Lab, UK
11:15 - 12:15
12:15
LUNCH
LUNCH
12:15 - 13:00
13:00
Small-angle neutron scattering
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Dr. Susana CM Teixeira, NIST Centre for Neutron Research, USA
Small-angle neutron scattering
Dr. Susana CM Teixeira, NIST Centre for Neutron Research, USA
13:00 - 14:00
14:00
Break & Discussion
Break & Discussion
14:00 - 14:15
14:15
EXERCISE: Fit of SANS data using SAS View
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Dr. Susana CM Teixeira, NIST Centre for Neutron Research, USA
EXERCISE: Fit of SANS data using SAS View
Dr. Susana CM Teixeira, NIST Centre for Neutron Research, USA
14:15 - 15:15
15:15
Break & Discussion
Break & Discussion
15:15 - 15:30
15:30
EXERCISE cont.
EXERCISE cont.
15:30 - 16:30
Wednesday 16 June 2021
08:45
Carbohydrates
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Dr. Marta Martinez Sanz, CIAL-CSIC, Madrid, Spain
Carbohydrates
Dr. Marta Martinez Sanz, CIAL-CSIC, Madrid, Spain
08:45 - 09:45
09:45
Break & Discussion
Break & Discussion
09:45 - 10:00
10:00
Lipids and lipid self-assembly
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Dr Hanna Barriga, Karolinska Institutet (KI), Stockholm, Sweden
Lipids and lipid self-assembly
Dr Hanna Barriga, Karolinska Institutet (KI), Stockholm, Sweden
10:00 - 11:00
11:00
Break & Discussion
Break & Discussion
11:00 - 11:15
11:15
Dynamics of concentrated protein solutions
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Prof. Anna Stradner Lund University, Sweden
Dynamics of concentrated protein solutions
Prof. Anna Stradner Lund University, Sweden
11:15 - 12:15
12:15
LUNCH
LUNCH
12:15 - 13:00
13:00
Glycosylation, lectins and molecular recognition
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Dr. Anne Imberty CNRS, Unversité Grenoble Alpes, France
Glycosylation, lectins and molecular recognition
Dr. Anne Imberty CNRS, Unversité Grenoble Alpes, France
13:00 - 14:00
14:00
Break & Discussion
Break & Discussion
14:00 - 14:15
14:15
EXERCISE: SLD of cellulose and agarose and how it can be affected by OH/OD exchange
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Dr. Marta Martinez Sanz, CIAL-CSIC, Madrid, Spain
EXERCISE: SLD of cellulose and agarose and how it can be affected by OH/OD exchange
Dr. Marta Martinez Sanz, CIAL-CSIC, Madrid, Spain
14:15 - 15:15
15:15
Break & Discussion
Break & Discussion
15:15 - 15:30
15:30
EXERCISE: Planning a SANS experiment with protein lipid interactions
-
Dr Hanna Barriga, Karolinska Institutet (KI), Stockholm, Sweden
EXERCISE: Planning a SANS experiment with protein lipid interactions
Dr Hanna Barriga, Karolinska Institutet (KI), Stockholm, Sweden
15:30 - 16:30
Thursday 17 June 2021
08:45
Methodology and applications of biomolecular simulations
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Prof. Ilpo Vattulainen, University of Helsinki, Finland
Methodology and applications of biomolecular simulations
Prof. Ilpo Vattulainen, University of Helsinki, Finland
08:45 - 09:45
09:45
Break & Discussion
Break & Discussion
09:45 - 10:00
10:00
Cell surfaces and membrane mimics
-
Motomu Tanaka, Univ of Heidelberg DE / Kyoto Univ JP
Cell surfaces and membrane mimics
Motomu Tanaka, Univ of Heidelberg DE / Kyoto Univ JP
10:00 - 11:00
11:00
Break & Discussion
Break & Discussion
11:00 - 11:15
11:15
Deuteration can advance solid state and solution state NMR to complement structural biology of membrane protein
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Prof. Anthony Watts, University of Oxford, UK
Deuteration can advance solid state and solution state NMR to complement structural biology of membrane protein
Prof. Anthony Watts, University of Oxford, UK
11:15 - 12:15
12:15
LUNCH
LUNCH
12:15 - 13:00
13:00
Lipid deuteration, internal membrane contrast and lipolytic enzymes
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Dr. Hanna Wacklin-Knecht, ESS ERIC, Lund, Sweden
Lipid deuteration, internal membrane contrast and lipolytic enzymes
Dr. Hanna Wacklin-Knecht, ESS ERIC, Lund, Sweden
13:00 - 14:00
14:00
Break & Discussion
Break & Discussion
14:00 - 14:15
14:15
Cell surfaces and membrane mimics
-
Dr. John Katsaras, Oak Ridge National Laboratory, TN, USA
Cell surfaces and membrane mimics
Dr. John Katsaras, Oak Ridge National Laboratory, TN, USA
14:15 - 15:15
15:15
Break & Discussion
Break & Discussion
15:15 - 15:30
15:30
EXERCISE: Planning experiment to reveal domain formation in a model biomembrane.
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Dr. John Katsaras, Oak Ridge National Laboratory, TN, USA
EXERCISE: Planning experiment to reveal domain formation in a model biomembrane.
Dr. John Katsaras, Oak Ridge National Laboratory, TN, USA
15:30 - 16:30
Friday 18 June 2021
08:45
Lipid nanoparticles for mRNA delivery
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Dr. Marianna Yanez Arteta, AstraZeneca Gothenburg, Sweden
Lipid nanoparticles for mRNA delivery
Dr. Marianna Yanez Arteta, AstraZeneca Gothenburg, Sweden
08:45 - 09:45
09:45
Break & Discussion
Break & Discussion
09:45 - 10:00
10:00
Imaging in life science
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Dr. Sophie Le Cann, Univ Paris-Est Créteil Val de Marne, France
Imaging in life science
Dr. Sophie Le Cann, Univ Paris-Est Créteil Val de Marne, France
10:00 - 11:00
11:00
Break & Discussion
Break & Discussion
11:00 - 11:15
11:15
The air-liquid interface to study drug interactions
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Dr. Richard Campbell, University of Manchester, UK
The air-liquid interface to study drug interactions
Dr. Richard Campbell, University of Manchester, UK
11:15 - 12:15
12:15
LUNCH
LUNCH
12:15 - 13:00
13:00
TUTORIAL: How to write a good beam time proposal!
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Dr. Richard Campbell, University of Manchester, UK
TUTORIAL: How to write a good beam time proposal!
Dr. Richard Campbell, University of Manchester, UK
13:00 - 14:00
14:00
Break & Discussion
Break & Discussion
14:00 - 14:15
14:15
EXERCISE: Image analysis on real data to extract structural parameters
-
Dr. Sophie Le Cann, Univ Paris-Est Créteil Val de Marne, France
EXERCISE: Image analysis on real data to extract structural parameters
Dr. Sophie Le Cann, Univ Paris-Est Créteil Val de Marne, France
14:15 - 15:15